chemReactor GR / CR
Multipurpose glass pilot reactor and pilot plant
Glass / glass lined reactor: 15 / 30 / 60 / 100 / 160 / 250 liter
Pressure: -1.0 (FV) to +0.5 bar
Temperature: -60°C (-90°C) to +200°C
Material: Borosilicate glass 3.3 / glass lined steel / PTFE / PFA / Tantalum
- Other setups are available.
Performance and reliability are key issues in the explosion proof design of Büchi glass reaction systems: The inert materials allow safe processing in a inert atmosphere of a wide range of solvents and acids in a completely sealed glass reaction system under full vacuum. Multiple chemical reaction steps are performed safely in the same setup. Processes can be easily improved by visually observing the reaction through the glass.
The GR / CR type chemReactor is a multipurpose pilot reactor system for chemical process development, scale-up, process simulation and kilo-scale cGMP production in batch and semi-batch operation.
We offer complete solutions for chemical processing including accessories like sampling devices, pH probes, rectification columns with structured packings, process monitoring and control as well as auxiliary equipment like temperature control units, nutsch filters / dryers, scrubbers or mixing vessels.
Standard package
- Jacketed full glass / glass lined steel reactor
- Multipurpose glass distillation overhead
- Stainless steel frame, supporting flexible glass superstructure
- ATEX Zone 1 (0) / CE / cGMP
- CIP capable
- FDA conform, highly corrosion resistant
- Complete documentation
Standard options
- Reactor lift for easy opening (vessel cleaning)
- Sampling device
- pH monitoring and control
- Gas introduction (Nitrogen purging and active gas)
- Vacuum / exhaust piping
- Additional feeders / receivers
- Solid feeding
- Cryogenic vessel for low temperature chemistry (-90°C)
- IQ / OQ / PQ
Distillation glass overhead
- Feed vessel for liquid addition
- Distillation column / vapor duct with pressure gauge and bursting disc
- Spiral condenser with vacuum / exhaust connection
- Vertical condensers or horizontal setup (compact design)
- Receiver vessel for collection of distillate
- Dean stark phase separator
- Vacuum / pressure equalization and distribution
- Self-draining «büchiflex» glass piping
Examples
Typical applications
- Vacuum distillation
- Azeotropic distillation (phase separation)
- Evaporation to any desired consistency
- Multi-component reactions
- Gas introduction into liquid phase
- Extraction of multi phase mixture
- Crystallization
- Refluxing
- Multiple chemical reactions liquid/liquid, liquid/solid
- Low temperature chemistry















